By Michael Goodfellow (Eds.)
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Additional resources for Actinomycetes in Biotechnology
7-164. Academic Press, London. Goodfellow, M. and Haynes, J. A . (1984). Actinomycetes in marine sediments. In: Biological, Biochemical and Biomedical Aspects of Actinomycetes (L. Ortiz-Ortiz, L. F. Bojalil and Y. Yakoleff, eds), pp. 453-477. Academic Press, Orlando. Goodfellow, M. and Williams, E. (1986). N e w strategies for selective isolation of industrially important bacteria. Biotechnology and Genetic Engineering Reviews 4, 213-262. , Arima, K. and B e p p u , T. (1983). Screening of antifungal antibiotics according to activities inducing morphological abnormalities.
Griseus. , 1985a). Clones with resistance to high levels of kanamycin and, to a lesser extent, dibekacin, gentamicin and streptomycin were generated, even though the parental strain was sensitive to low levels of all of these antibiotics except streptomycin. The kanamycin resistance of one clone was 200-fold higher than that of the parent and stable even when the clone was exposed to low temperatures for a long period. If this change was to be studied at gene level, gene rearrangement or base substitution causing the enhanced expression of the resistance gene might be revealed.
D o b s o n , W. E . and Lenzini, M. D . (1985). Novel antitumor antibiotics CI-940 PD-114720 elactocin and PD-114721 hydroxyelactocin. Taxonomy, fermentation and biological activity. Journal of Antibiotics 38, 460-465. 32 R. D. N O L A N A N D T. CROSS Udaka, S. and Miyashiro, S. (1982). A new test system for screening macromolecular antitumor antibiotics and its application to culture fluids of actinomycetes. Journal of Antibiotics IS, 1312-1318. , Weiser, I. T. and Yannai, S. (1981). Bioluminescence test for mutagenic agents.
Actinomycetes in Biotechnology by Michael Goodfellow (Eds.)
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